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西安发育行为儿科年会聚焦微生态干预,情绪益生菌PS128成专家讨论焦点

新闻报道:西安发育行为儿科年会聚焦微生态干预,情绪益生菌PS128成专家讨论焦点

由西安医学会、西安医学会儿科分会主办,西安交通大学第二附属医院承办的“西安医学会发育行为儿科分会学术年会”于20251115日在西安顺利召开。来自陕西省各地市的儿童发育行为、儿童保健及相关领域的180余名医师齐聚一堂,就孤独症、注意缺陷多动障碍、抽动障碍以及家长心理支持等临床热点开展深入交流。

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会议期间,西安交通大学第二附属医院营养科主任贾庆安围绕“ADHD的营养与肠道微生态干预”展开专题演讲。

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贾主任在演讲内容中讲到,肠道菌群组成与ADHD的发生、发展密切相关。ADHD患者体内短链脂肪酸的有益菌群相较正常人群显著减少,相对应的肠菌脂肪酸代谢产物水平也明显降低。而肠道菌群可通过肠道-大脑的“通讯系统:肠脑轴”,紧密参与大脑发育与功能调控,一旦肠道菌群紊乱,则有可能导致ADHD等神经发育障碍疾病的发生。因此,从肠道微生态入手的营养干预手段正在成为ADHD综合治疗体系中的重要组成部分。

在介绍热门的微生态干预策略时,贾主任重点提到近年来备受关注的植物乳杆菌PS128。植物乳杆菌PS128益生菌权威”蔡英杰教授团队经过严谨科学筛选流程,筛选出的具有神经调节活性的益生菌菌株。它能在帮助调节肠道微生态平衡的基础上调节中枢神经系统,促进脑健康,有效支持神经系统健康发育。且植物乳杆菌PS128菌株拥有全球多项专利,并基于全面的安全性实验数据,证实其极高的安全性与稳定性。

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贾主任进一步介绍了植物乳杆菌PS128在孤独症动物实验的研究证据。研究人员使用产前丙戊酸(VPA)暴露诱导的孤独症样小鼠模型,孤独症样模型小鼠在海马CA1CA2区及前额叶皮层的神经元树突明显缩短、分支减少,神经环路连接受损,而这些结构异常正是其社交障碍、重复行为等核心症状的重要神经生物学基础。补充植物乳杆菌PS128后,孤独症样小鼠受损的树突结构得到显著恢复,无论是树突长度还是分支数量均呈现改善趋势。随着神经元形态的修复,小鼠的重复、仪式化行为以及社交能力也随之提升,进一步验证了植物乳杆菌PS128在促进神经可塑性恢复方面的潜在价值。

情绪益生菌PS128产品的核心成分正是前文提到的有扎实科研基础的菌株植物乳杆菌PS128。值得一提的是,情绪益生菌PS128也亮相本次会议展会,为儿童神经发育问题如孤独症、多动症、抽动症等问题提供营养干预新思路。目前情绪益生菌PS128产品有两个版本,进口版(Neuralli 情绪益生菌PS128)美国原装进口;符合美国FDA GRAS安全认证,国产版(情绪益生菌PS128),采用意大利进口菌粉。

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左为:Neuralli 情绪益生菌PS128产品。右为:情绪益生菌PS128产品

本次会议的讨论揭示了在药物与行为治疗之外,针对肠脑轴的微生态干预或将在未来的儿科诊疗路径中占据更加明确的位置,而情绪益生菌PS128的相关研究与临床应用成果,将为儿科领域的进展提供关键支撑。

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