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浙大儿院竺智伟:情绪益生菌PS128可调节肠脑轴进而改善情绪问题

新闻报道:浙大儿院竺智伟:情绪益生菌PS128可调节肠脑轴进而改善情绪问题

7月13日—7月14日,浙江省神经科学学会第十二届学术年会盛大召开。本次会议设有主会场一个,主题分会场十个。其中,孤独症分会、神经病学分会、分子神经生物学分会荣获优秀分会,孤独症全生涯视角下的孤独症服务与研究主题分会场摘得最具人气主题分会场。

孤独症,也称自闭症,是一种起病于儿童早期且有可能持续终生的神经发育障碍性疾病,其特征包括社会交往障碍、言语和非言语交流障碍,以及局限、重复的行为和兴趣。这些特征使得孤独症患者在日常生活中面临诸多挑战,他们往往难以理解和回应他人的情感和社交信号,进而产生“孤独”的感觉。

那么如何走出这个困境?在《全生涯视角下的孤独症服务与研究》为主题的分会场上,来自神经科学领域相关基础及临床知名专家、学者纷纷介绍了当前孤独症最新的研究成果,为解析孤独症的神经发育指引了新方向。



浙江大学医学院附属儿童医院的竺智伟主任在会上带来了题为《精神益生菌PS128在ASD中的营养支持》的特邀报告演讲,为孤独症的辅助治疗提供了新的思路和方法。她指出:孤独症儿童具有高比例的胃肠道问题且更容易出现情绪、睡眠问题。

同时,竺智伟主任也指出:“孤独症的成因涉及多种因素,包括遗传因素、环境因素、母孕期不利因素及肠道菌群的失调。前三者通常难以改变且不可逆,而肠道菌群的失调相对可控。科学研究表明肠道菌群可通过生成具有神经活性的代谢产物而调控小鼠的行为,提示肠脑轴互动是孤独症发病和治疗的关键环节之一。对新生儿的跟踪研究也表明肠道菌群与神经发育障碍存在强烈关联。”



竺主任进一步解释了精神益生菌的作用机制。精神益生菌可以影响肠脑轴,调节肠道菌群,从而改善孤独症儿童的情绪和心理问题。她提到,精神益生菌PS128在临床研究中已经得到良好验证,能够调节肠脑轴,进而改善孤独症儿童的情绪心理问题。相关临床案例证明了PS128的有效性,并且不良反应相较其他益生菌组明显降低,具有高安全性,目前已在全球48个国家和地区得到广泛使用。



精神益生菌PS128因其在情绪调节的重要作用,也常称作情绪益生菌PS128。情绪益生菌PS128不仅在孤独症辅助治疗中表现出色,还被用于其他情绪和心理问题的管理,如多动症(ADHD)和抑郁症、焦虑症等等。在主题会现场,竺主任也分享了一些情绪益生菌PS128的家长反馈,展示了PS128在实际应用中的显著效果。



综上所述,肠道微生物的紊乱与孤独症疾病的发生发展密切相关,而情绪益生菌PS128可以作用于肠脑轴,调节身体的神经、免疫和内分泌系统,从而影响中枢神经系统及其相关功能,对于孤独症、多动症、抽动症等神经发育障碍疾病具有很好的治疗效果。未来,通过持续的科学探索和临床实践,也期待情绪益生菌PS128在情绪和神经健康管理领域开创更多的可能性。

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